photographer profile / NIAID
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NIAID scientist wears BSL-3 gear to demonstrate preparation of tissue culture plates infected with a chimera of West Nile virus and the dengue virus. The lab is developing a live, attenuated virus vaccine for West Nile virus. Credit: NIAID

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An illustration showing the steps in creating the flu vaccine. Scientists can custom-make a flu strain by assembling genes that code for the desired features. Credit: NIAID

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The goal of reassortment is to combine the desired HA and NA antigens from the target strain (flu strain 1) with genes from a harmless strain that grows well in an egg (flu strain 2). Illustration showing the flu virus containing eight gene segmen...

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An illustration of antigenic shift--the genetic change that enables a flu strain to jump from one animal species to another, including humans. Credit: NIAID

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Firey-looking electron micrograph of herpes simplex virus. Credit: NIAID

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Shingles rash caused by herpes zoster virus. Credit: NIAID

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Genetic relationships among human and swine influenza viruses, 1918-2009. Red arrows indicate human influenza virus lineages, black arrows swine influenza virus lineages, and gray arrows exportation of one or more genes from the avian influenza A ...

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NIAID scientists confer in the laboratory about HIV gene regulation. Credit: NIAID

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 In 1891, after four years on Staten Island, New York, the Hygienic Laboratory moved to Washington, DC, where it occupied the top floor of the Butler Building on Capitol Hill. Credit: National Library of Medicine, NIH

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When ferritin (gray) is fused with the influenza protein hemagglutinin (blue), it self-assembles into a sphere with eight protruding spikes from its surface.

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NIAID scientists studying the human immune response to HIV. Credit: NIAID

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Scanning electron micrograph of HIV particles infecting a human H9 T cell, colorized in blue, turqoise, and yellow. Credit: NIAID

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An illustration showing the sand fly and human stages of leishmaniasis.

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In 1901 Congress appropriated funds for a new building for the Hygienic Laboratory and provided a five-acre site on the old Naval Observatory grounds at 25th and E Streets, N.W, in Washington, DC. The building was completed in 1904 but soon proved...

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 In 1887, Dr. Joseph Kinyoun set up his one-room Hygienic Laboratory in the Marine Hospital on Staten Island in New York to research cholera and other infectious diseases such as diphtheria, typhoid, smallpox, typhus, plague and tuberculosis. This...

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U.S. Marine Hospital No. 21 in Stapleton, Staten Island, New York. The one-room Hygienic Laboratory, forerunner of the National Institutes of Health, was located in this building. Credit: National Library of Medicine, NIH

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Public Health Service physicians checking immigrants arriving to the United States for signs of illness. The immigration law of 1891 made it mandatory that all immigrants coming into the United States undergo health inspection by Public Health Ser...

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Scanning electron micrograph of MRSA bacteria (yellow) being ingested by a neutrophil (purple). Credit: NIAID

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Red arrows indicate human influenza virus lineages, black arrows swine influenza virus lineages, and gray arrows exportation of one or more genes from the avian influenza A virus gene pool. Horizontal bars shown inside the virus represent each of ...

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Colorized scanning electron micrograph of red blood cell infected with malaria parasites, which are colorized in blue. The infected cell is in the center of the image area. To the left are uninfected cells with a smooth red surface. Credit: NIAID

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